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Gilead, Galapagos Announce Positive Phase 2 Results

In the TORTUGA study of filgotinib, an investigational, selective JAK1 inhibitor for the treatment of ankylosing spondylitis

Gilead Sciences and Galapagos NV announced that the randomized, placebo-controlled Phase 2 TORTUGA study of filgotinib, an investigational, selective JAK1 inhibitor, achieved its primary efficacy endpoint in adults with moderately to severely active ankylosing spondylitis (AS).    In the study, patients treated with filgotinib achieved significantly greater improvements in AS Disease Activity Score (ASDAS), the primary endpoint, at Week 12, with a mean change from baseline of -1.5 versus...

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